Harold Minkowitz, MD: Scientific & Clinical Architect

Dr. Minkowitz is a board certified Anesthesiologist.  He began his professional career as an Assistant Professor of Anesthesiology at the University of Texas Health Science Center at Houston.  He has since left the University setting to practice at Memorial Hermann Memorial City Medical Center where he currently maintains active staff status.

In addition to his clinical practice, Dr. Minkowitz has always had a keen interest in clinical research.  This began during his residency training, and has been his passion throughout his career.  He is now in his third decade of being involved in clinical research.  He specializes in acute perioperative clinical studies, with an emphasis on acute pain.  He has an understanding of the operational challenges involved with completing these trials in an expedient manner.


Mark Sacaris: Strategy

Mark’s career started in the financial services industry after college, where he spent several years with a boutique investment management firm.
In 1990, Mark transitioned into the pharmaceutical industry, going to work with Rhone-Poulenc Rorer Pharmaceuticals as a pharmaceutical and hospital sales representative and regional acute care manager in the Midwest. Ready for his next challenge, Mark moved into marketing with RPR as a marketing manager for an emerging drug called Lovenox. Along with a small marketing team that managed the brand, Mark was responsible for several sNDA launches, treatment of DVT and PE, Long-term Hip Replacement Prophylaxis as well as managing the day to day hip and knee replacement franchise. In 2000 Mark moved to San Diego to work in the area of hematological malignancies for Ligand Pharmaceuticals. During his time at Ligand, Mark was initially responsible for a diphtheria toxin (Ontak) and then eventually in charge of the Marketing Department that was responsible for Ontak, Targretin Capsules and Gel, Panretin Gel, and Avinza.
In August of 2001 Mark and his business partner launched OnPoint Resources, a medical communications and education company dedicated to serving the pharmaceutical, biotech, and medical device industries. This venture expanded into several other medical communication companies, including Tracxion World Medical and Center for Healthcare Education and Research, Inc. (CHE). CHE is a full service medical communications and education organization dedicated to the pharmaceutical, biotech, and medical device industries. It has evolved into its current business model allowing it to engage leaders in many therapeutic areas and to play a role in launching blockbuster drugs. In addition, CHE helps companies reposition existing products and assists clients build strategies around evidence based medicine to increase the success of their current product or portfolio. CHE has developed several educational initiatives, such as the creation of a heart failure nursing society, as well as transformed the educational platform of an existing orthopaedic society, effectively expanding its reach from a singular, U.S. based vision into a worldwide educational organization and powerful content distribution portal in the global orthopaedic community.



C3 Staff

C3 taps into its vast store of data management, clinical data analysis, web and mobile application design, media production, KOL consulting network, pharmaceutical and biotech relationships, communications, and educational training resources as needed for each project.