Harold Minkowitz, MD: Scientific & Clinical Architect

Dr. Minkowitz is a board certified Anesthesiologist.  He began his professional career as an Assistant Professor of Anesthesiology at the University of Texas Health Science Center at Houston.  He has since left the University setting to practice at Memorial Hermann Memorial City Medical Center where he currently maintains active staff status.

In addition to his clinical practice, Dr. Minkowitz has always had a keen interest in clinical research.  This began during his residency training, and has been his passion throughout his career.  He is now in his third decade of being involved in clinical research.  He specializes in acute perioperative clinical studies, with an emphasis on acute pain.  He has an understanding of the operational challenges involved with completing these trials in an expedient manner.


Mark Sacaris: Strategy

Mark’s career started in the financial industry with Criterion Funds, a boutique investment management firm.  After 3 years with Criterion, Mark transitioned into the pharmaceutical industry, going to work with Rhone-Poulenc Rorer Pharmaceuticals in 1991.  He spent 5 years in field and hospital sales before managing the midwest region as a hospital sales manager.  In 1995 Mark moved into marketing with RPR as a marketing manager on the eventual blockbuster anticoagulant, Lovenox. Mark was responsible for several sNDA launches as well as the hip and knee replacement indications.  In 1999 Mark  moved to San Diego to work in the area of hematological malignancies for Ligand Pharmaceuticals. During his time at Ligand, Mark was initially responsible for a diphtheria toxin and then eventually in charge of the Marketing Department.

In  August of 2001 Mark and his business partner launched the Tier1Group of companies, which included strategic marketing and medical communications companies, Traxcion World Medical and OnPoint Resources . Shortly after, CHE (Center for Healthcare Education) was created.  CHE is a full service medical communications and education organization dedicated to the pharmaceutical, biotech, and medical device industries.  Tier1Group now serves the strategic marketing and medical communications side of the business. Both companies have evolved into their current business models allowing them to engage leaders in many therapeutic areas and play a role in launching blockbuster drugs, repositioning existing products and assisting clients build strategies around evidence based medicine to increase the success of their current product or portfolio.  CHE also serves the role as an association management company for the International Congress for Joint Reconstruction (ICJR.com).  He currently serves as the Chief Operation Officer of this global, membership based organization that delivers high, quality orthopaedic education around the globe.



John Nelson: Insight & Marketing Leader

John has 25 years pharmaceutical experience including stints with Bayer, Cephalon, Sanofi, JNJ. Additional senior leadership experience in Medical communications & Healthcare advertising both boutique and fortune 50 firms has allowed John a 360 degree view throughout the pharmaceutical industry. His professional experience includes sales, sales training, market research and product marketing. This experience translates into the ability to define, formalize & execute on pre-launch, launch, and post launch strategies. His therapeutic category experience is broad yet deep in Infectious diseases, cardiovascular disease, CNS, AutoImmune, Hematology/Oncology & several Orphan diseases. 

Additionally, Johns insights and experience in patient advocacy and development of technology platforms exclusively in the pharmaceutical vertical provide C3 a valuable resource not only in the strategy area but also leveraging newer technology to customers.


C3 Staff

C3 taps into its vast store of data management, clinical data analysis, web and mobile application design, media production, KOL consulting network, pharmaceutical and biotech relationships, communications, and educational training resources as needed for each project.